Osteopontin as two-sided mediator of intestinal inflammation
نویسندگان
چکیده
منابع مشابه
Osteopontin as two-sided mediator of intestinal inflammation
Osteopontin (OPN) is characterized as a major amplifier of Th1-immune responses. However, its role in intestinal inflammation is currently unknown. We found considerably raised OPN levels in blood of wild-type (WT) mice with dextran sodium sulfate (DSS)-induced colitis. To identify the role of this mediator in intestinal inflammation, we analysed experimental colitis in OPN-deficient (OPN(-/-))...
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ژورنال
عنوان ژورنال: Journal of Cellular and Molecular Medicine
سال: 2009
ISSN: 1582-1838,1582-4934
DOI: 10.1111/j.1582-4934.2008.00428.x